Rapid delivery of diverse peptides from mg to multigram scale
Sai Life Sciences has extensive experience across peptide synthesis, purification and characterization and leverages this experience to accelerate peptide drug discovery programs across different collaborations.
Peptide Synthesis - Sai Life Sciences
Sai Life Sciences offers a range of services in peptides from
delivery of mg to multigram scale. Peptides are produced
using solution and solid phase synthesis with use of
automated &/or manual synthesizers.
Expertise
- Linear and cyclic peptides
- N-terminal/Side chain modifications, e.g.
- Acylation, Biotinylation, Fluorescent & Dye
- C-terminal modifications
- Alkylated carboxamides, Alcohols, thioesters
- Conjugations: DOTA, Lipid’s/mPEG’s, payload/linkers
- Cyclic peptides: Disulfide, RCM, Lactam, Thioethers
- Peptide libraries synthesis
- Incorporation of unnatural amino acids: side chain modified,
N-methylated, D-amino acids, in peptide sequences
- To download the flyer PDF, click here.
- To know more about our services, do get in touch!
Integrated Peptide Discovery
Infrastructure
- Fully automated parallel synthesizer’s
- Syro-I/II, Multipep-2, Microwave CEM Liberty Blue
- Support for gram scale synthesis: manual peptide
synthesizers (100 mL to 2 L reaction vessels)
Dedicated Purification - Characterization
State-of-the-art purification and analytical characterization platform
- Purification:
- UV prep HPLCs (Waters, Shimadzu, Knaur)
- MS directed prep-HPLCs (Waters)
- RP-MPLCs (Biotage, Teledyne)
- DAC columns
- Reverse Phase Analysis: Multiple HPLCs (Waters)
- Mass Characterization:
- PDA/MS (Shimadzu)
- UPLC/LC-MS (Waters)
- Ion trap, ELSD (Agilent)
- MALDI-TOF (Thermo Fischer)
- Freeze/tray Dryers (Vertis, Labconco, Martin Christ)
- CD, UV-Vis spectrometers