Blog

On the World Environment Day, we reflect on the efforts we’ve taken towards sustainability. A year ago, on June 5th, 2023, Sai Life Sciences renewed its Sustainable Development Goals (SDGs), charting a roadmap to achieve specific environmental, social, and governance (ESG) targets by FY27, with FY22 as the baseline year. Three of these SDGs pertain […]

In the 1936 Charlie Chaplin movie “Modern Times”, we see several hilarious attempts by the Management of Electro Steel Corp at raising the productivity of their factory workers, ranging from speeding up their assembly line to deploying a robotic feeding machine to keep them working even during lunch. While the movie is exaggerated to prove […]

Mixing in a multiphase system, especially in a scale-up environment, can prove to be an uphill task. A thorough understanding of mixing patterns is crucial as it enables the optimization of process parameters, reactor design, and operational conditions. It also aids in controlling phase separations and preventing undesirable side reactions. Process engineers are leveraging simulation […]

The developability assessment of new chemical entities (NCEs) is a crucial step in the drug discovery and development cycle. It involves an evaluation of a potential lead candidate’s/compound’s chances of becoming a clinical drug candidate at an early phase. The goal is to characterize the clinical drug candidate, identify, and address any potential challenges that […]

When MS Dhoni in his inimitable style flicks one over the ropes, our hearts collectively skip a beat. The answer of this phenomenon, that is being experienced by millions of cricket enthusiast this IPL season, lies in electrophysiology, the study of electrical properties of cells and tissues. In drug discovery process, electrophysiology has the potential […]

Solving tough scientific challenges is our raison d’etre. This often leads us along under-explored paths that are both challenging and exciting. One of the sophisticated particle design techniques that is used to improve an API particle’s ‘flow property’, among other physical properties, is Spherical Agglomeration. This technique is considered to be a complex one – […]

The criticality of Crystallisation process in the manufacture of drug substancesThe importance of crystallisation in the pharmaceutical and high-value chemical industries has increased recently due to many technical and commercial factors in last decade: Requirements to reduce impurities from quality standpoint Better yields from business standpoint, The need to crystallise difficult-to-crystallise small / macro-molecules from […]

Outsourcing of R&D and Manufacturing has seen over a 50% budget increase in 2021, according to a report by CPhI, the record number of investments in discovery pipelines coupled with broader macro factors is going to drive huge growth for CDMOs in the next 2-3 years. Full-service CDMOs, both large and medium scale, are looking […]

What is High Throughput Screening? The virtue of HTS If a methodology has to be nominated to the Science Hall of Fame for its contributions in the field of Biology and Chemistry and its interfaces, this is with no doubt High Throughput Screening (HTS). The concept is simple: testing large libraries of entities -compounds, biologicals […]