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Comprehensive Solutions from Development to Commercialization

Sai Life Sciences offers end-to-end services for Antibody-Drug Conjugate (ADC) development and manufacturing, encompassing linkers and payloads. Our expertise spans the entire molecular lifecycle, from early development to commercial scale, with a focus on high-potency handling and innovative solutions.

Key Expertise Areas

  • Attachment Site Optimization
  • Linker Design & Synthesis
  • Cytotoxic Payload Development & Manufacturing

Sai specializes in payloads, with High Potency Labs and High Potency Block, and extensive expertise in handling such chemistry

HPAPI Manufacturing in Bidar: 16,000 sq. ft. block
designed and validated to handle high potent molecules
less than 0.1 μg/m3

HPAPI, Linkers and Lipid Capabilities

HPAPI & Payloads

  • Dedicated HPAPI lab in Hyderabad:
    • Containment to < 1 μg/m3
    • Streamlined workflow: Dispensing, Reaction,
      Purification, Drying, Packing
    • Advanced safety features: Isolators, fume hoods,
      HEPA filtration, wet scrubbers
  • Payload manufacturing in Bidar:
    • 0.1 μg/m³ OEL handling
    • Comprehensive capabilities: Storage, isolated
      sampling, powder processing, flow chemistry,
      chiral synthesis, advanced chromatography

High Potency Capabilities

  • OEL 4 & OEL 5 (0.1 μg/m³) handling in dedicated labs
    (Hyderabad & Bidar)
  • HPAPI handling and development